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Nature of the Discipline
The Department of Biochemistry and Molecular Biology integrates the molecular
life sciences from the most basic biology-chemistry interface to molecular genetics
and bioinformatics. The disciplines of the molecular biosciences involve the use
of sophisticated analytical, biochemical, and genetic technologies to examine the
activities of living systems, focusing on the structures and roles of macromolecules
in complex biological systems.
Faculty members in biochemistry function as research project managers and principal
investigators of their own individual programs whose success require them to be
innovative and interactive with other scientists. The faculty member designs the
individual research programs, and there is little to no administrative direction
applied to their choices of research activities.
Each faculty
member is expected to direct an active research program or be involved in other
scholastic activities involving the training of doctoral and masters-level
graduate students as well as undergraduate students studying in biochemistry and
molecular biology.
In addition, each tenure-tract faculty member provide effective formal classroom
teaching, provides service to the department's research and academic
functions, and maintains research/teaching funding to sustain their laboratory
programs.
The Department
has multiple missions that involves balancing teaching in biochemistry and
molecular biology with the needs of high-achieving undergraduate majors in
biochemistry (363 students),
a growing Ph.D. graduate program (35 students) in biochemistry, and of highly competitive
research programs. The Department has administrative responsibility for the support
and resource management for the interdepartmental Graduate Faculty of Biotechnology
and Cell & Molecular Biology.
Mission
The mission of the Department of Biochemistry and Molecular Biology is to provide
strong educational programs for undergraduate, graduate and professional students,
to conduct high quality research in biochemistry, molecular biology and biotechnology,
and to effectively transmit scientific knowledge to the general public.
Vision
Biochemistry has taken the forefront in defining broadly based opportunities in
biotechnology processes and applications that indicate the path for the biologically
based future of the twenty-first century. This future will influence all phases
of our lives from the
quality of food
and fiber to the preservation of natural resources and the medical biosciences.
The molecular tools, which are being developed today, will lead to technologies
to manage infectious diseases, cure metabolic and cellular dysfunction, and define
the physical quality of life. This Department must provide a broad set of technical
and conceptual capabilities that result in a cutting-edge perspective to discern
the molecular events that underlie normal and aberrant life science functions in
medicine, nutrition, agriculture, and environmental adaptation. In addition, the
Department must be involved in the promoting life-long education and technology
transfer necessary to disperse this information.
Facilities
Research at UNR's Department of Biochemistry and Molecular Biology utilizes state-of-the-art
approaches to recombinant DNA technology, gene transfer methodologies, chromosome
analysis, microscopy, electrophysiology, biochemical isolation and analysis of proteins
and nucleic acids and crystallography much of which is conducted at the
Protein Core Facility .
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Facilities are
available for analysis of biological samples, including electron microscopy, confocal
microscopy, optical biology, flow cytometry, and histology.
- In addition, facilities for cell-oriented studies include monoclonal antibody production,
construction of viral vectors, and transgenic mouse generation.
- Manipulation of cells is central to many research programs and includes such techniques
as micro-injection and patch clamping for neurophysiology and laser manipulation
for cytogenetics.
- Structural research on campus employs x-ray crystallography, mass spectrometry,
and DNA and protein sequence analysis.
- Also, oligonucleotide and peptide synthesis services are available on campus, as
are facilities for micro-array analysis.
- The Nevada Genomics Center offers
one of the best DNA purification/quantitation services, along with sequencing reactions
and analysis, fragment analysis, microarrays and PCR services.
- The Center for Bioinformatics is the
States' premier center of Bioinformatics.
- Campus laboratories are linked to one another and to the worldwide research community
by dual T1 fiber optic communications networks.
- A supercomputer and SUN-UNIX workstation on campus are used for data analysis and
molecular modeling.
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